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Because the bodys largest natural pulse of growth hormone is released during the first few hours of deep sleep

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doi: 10.1111/j.1399-3038.2007.00625.x Summary Keywords autoimmunity, chromatin, epigenetics, histone modifications, hypogammaglobulinemia, immunology, infection, neurodevelopmental disorders Citation Jans D, Al B, Bouman A, Geelen JM, Kleefstra T and Placek K (2026) Clinical immunology in chromatinopathies: a scoping review

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