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Experimental results from in vitro and in vivo studies found no evidence of LC toxicity (Rebouche, 2004)
Conversely, we also supplemented either specific BCFAs or a mixture of them to the OP50 culture but were not able to increase the BCFA levels above 30%, likely because OP50 could not take in large amount of BCFAs (Figure S2C)
In case of LCHAD/MTP deficiency and symptomatic VLCAD deficiency, MCT at 2025% of energy intake, and total fat at 2535% of energy intake is advised [143]
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