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Patients should understand that individual responses may vary and that lack of response should prompt reassessment of the treatment approach rather than unlimited dose escalation

Following the use of tanezumab, a clinical trial reported an improvement in pain scores as well as enhanced function and overall evaluation outcomes in individuals with chronic painful disorders, not including IC [33,34,35]

whilst alcohol swabs are not always necessary for patients with good hygiene, they may be used if preferred

But, for those who have trouble sleeping, the issue can also be incredibly frustrating and lead to a vicious cycle

A sore, swollen, or unusually pale tongue can also be a tell-tale sign