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Lyme disease spirochaetes possess an aggrecan-binding protease with aggrecanase activity

On the one hand, NF2 reduces degradation of large tumor suppressor homolog 1/2 (LATS1/2) by inhibiting the E3 ubiquitin ligase CRL4 DCAF1 (Li et al 2014)

Akaike, T., Motohashi, H., Fukuto, J

Milk exosome-liposome hybrid vesicles with self-adapting surface properties overcome the sequential absorption barriers for oral delivery of peptides
