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As for non-small cell lung cancer (NSCLC), mutations in the epidermal growth factor receptor render these cancer cells highly dependent on cysteine supply

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The datasets were all generated from the ROSMAP cohort, these included the single cell transcriptomic data from the prefrontal cortex region (snRNAseqPFC_BA10) (Syn18485175) 52 ( bulk RNA-seq data of dorsolateral prefrontal cortex (DLPFC), posterior cingulate gyrus (PCG), and anterior cingulate (AC) regions (syn3388564) 134 ( and the non-targeted metabolomics data form DLPFC region (syn3157322) ( Key clinical and pathological features of de-identified subjects included in these studies can be found in Supplementary Data 1

doi:10.1158/1940-6207.CAPR-11-0306