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425 million adults between the ages of 30 and 69 have moderate to severe OSA (15 or more events per hour), which is a condition that affects 1 billion people globally

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All manipulations were performed according to the manufacturers protocols

The release of cytochrome C from the mitochondria leads to production of a caspase-activating complex of cytochrome c, APAF-1, and procaspase-9, triggers the up-regulation of caspase-9, and subsequently increases the expression of caspase-3, followed by the induction of apoptotic events in the cell [44]

Ann Neurol 14:471479