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The scientists carrying out these studies (Cutting, Tainter and colleagues at Stanford University) warned of the potential side-effects and the small margin for safety, but firms started selling DNP directly to customers, so people were taking it without medical supervision
The functional genotype of glutathione S-transferase T1 gene is strongly associated with increased risk of idiopathic infertility in Russian men

doi: 10.1016/j.bbi.2007.01.001 55 GabrM

A further study examined whether SAMe could delay neuropathology in 3Tg-AD mice, which harbor mutant genes for human APP, PS-1, and tau, here showing that SAMe supplementation in the diet did, in fact, reduce extracellular A deposits [196]
[DOI] [PubMed] [Google Scholar] 154.Moens U., Kostenko S., Sveinbjrnsson B