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Description
Reduction of the degree of cerebral edema in rats with global cerebral ischemia-reperfusion injury, relieves the metabolism abnormity of free radical and improves the function of cognition [88]

After CTR1-mediated copper transfer into the cytoplasm, CTR1 shuttles copper to the copper chaperones cytochrome c oxidase copper chaperone (COX17), copper chaperone for superoxide dismutase (CCS) and antioxidant 1 (ATOX1) 20,21

It removes a barrier, which is fatigue and reduced physical capacity

In seneszenten Zellen jedoch bindet FOXO4 an p53 und verhindert so diese natrliche Selbstzerstrung

The PI3K/Akt/mTOR pathway is implicated in the premature senescence of primary human endothelial cells exposed to chronic radiation
