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During this process, NOX-2 is assembled in a phagosome during the phagosome maturation stage and accelerates the reaction of NADPH with molecular oxygen to produce NADP + , protons, and O 2

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Cancer Metastasis Rev 38(12):205222 Rajeshkumar NV, Yabuuchi S, Pai SG et al (2017) Treatment of pancreatic cancer patient-derived xenograft panel with metabolic inhibitors reveals efficacy of phenformin
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