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In another embodiment the buffer is a sodium phosphate dibasic buffer having a pH of about 7.0 to about 8.5
Clinical and animal studies have demonstrated that a major physiological consequence of total parenteral nutrition is the loss of intestinal barrier integrity.52 Mice administrated with total parenteral nutrition show increased intestinal paracellular permeability and decreased levels of TJ proteins, which is reversed by IL-10 treatment.53 Collectively, IL-10 restores the intestinal barrier defect

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