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Sporer, K

[ There is still a controversy whether high UA is a compensatory mechanism to overcome increased oxidative stress, which is an independent cause of cardiovascular disease [ and is a component of the inflammatory process

However, when the body lacks the necessary cofactors to drive these reactions, the entire system begins to slow down, leading to a cascade of systemic dysfunction

Several studies using non-invasive physiological markers, such as reduced ABR wave-I amplitude, suggest an association between cochlear synaptopathy and tinnitus, particularly in individuals with normal audiograms 11,43,61,62

J Neurochem 101:120513 Kidd PM (2003) Glutathione: Systemic protectant against oxidative and free radical damage