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Mutating any of these three residues has been shown to completely abolish both the lipase and esterase activities of MGL (57)
If you have the MTHFR C677T variant, be sure to look for a B-complex that includes methylfolate instead of folic acid along with the other active forms of B vitamins
Aging 32 , 21902197 (2011)
Insulin resistance across the spectrum of nonalcoholic fatty liver disease
The best choice depends on your specific situation, lab values, and health status
