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However, when they become damaged or loose, the gut becomes hyper-permeablea state commonly referred to in functional medicine as "leaky gut" or clinically as intestinal permeability

Professional opinion on this issue has trended toward skepticism because studies have varied widely in terms of study length, sample size, methodological consistency, and artificial food dyes which varied in amounts and dyes selected (Stevens, Kuczek, Burgess, Hurt, & Arnold, 2011)

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