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Therefore, measuring the levels of MMA in the blood can help diagnose a vitamin B-12 deficiency, especially in an early, asymptomatic state

Rutchik et al., 2012

[DOI] [PMC free article] [PubMed] [Google Scholar] 124.Girgis R.R., Baker S., Mao X., Gil R., Javitt D.C., Kantrowitz J.T., Gu M., Spielman D.M., Ojeil N., Xu X., et al
doi: 10.1016/j.chroma.2016.02.016

Some studies suggest that MR may impair T-cell function under certain conditions, and long-term restriction could lead to complex metabolic feedback