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It penetrates the cell membrane and disrupts internal cellular function, leading to regulated cell death

In addition, GDH inhibition also limits synaptic glutamate uptake (Whitelaw and Robinson 2013), whereas genetic deletion of GDH leads to impaired glutamine metabolism in cultured neurons (Hohnholt et al

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Boules M, Li Z, Smith K, et al (2013) Diverse roles of neurotensin agonists in the central nervous system

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