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They are currently widely used in the study of glaucoma (Sayyad et al., 2017), macular degeneration (Huang et al., 2022), intraretinal neurodegeneration (Kunimi et al., 2021), and blue light induced retinal lesions

CPE cells are connected by tight junctions, which are responsible for maintaining barrier integrity

Given the complexity of the ECS and its involvement in various physiological processes, ongoing research, particularly on compounds like CBD, holds promise for unlocking novel therapeutic strategies across multiple medical fields

Data acquisition was performed by investigators blinded to experimental groups

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