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2) It is important to note that ASA is toxic, as amygdalin can be metabolized by -D-glucosidase, leading to cyanide poisoning
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The remaining 5% of absorbed acetaminophen is oxidized by cytochrome enzymes, mainly CYP2E1, to produce N -acetyl-p-benzoquinoneimine (NAPQI), a highly reactive and short-lived oxidation product or electrophile (Figure 3) (13,51)

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10.1158/1541-7786.MCR-19-0691 Mol
