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Description
Hypoxia promotes EV secretion by impairing lysosomal homeostasis in HNSCC through negative regulation of ATP6V1A by HIF-1

PMID: 10370861.
Once protonated, the peptide disrupts endosomal membranes, destabilizing endosomes

Cancer 69 , 142150 (2016)

Levels of trkA and BDNF mRNA, but not NGF mRNA, fluctuate across the estrous cycle and increase in response to acute hormone replacement
