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Microfracture technique for full-thickness chondral defects: technique and clinical results

The requirement of medications as first-line treatment for these chronic conditions increases the potential cost of treatment, leaving older adults in a polypharmacy dilemma and causing many negative effects

1, highlighting the shift from type III to type I collagen and the alignment of collagen fibers
& Smith, C.J
2003 Oct 8;23(27):9185-93
