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Improved Stability: The phospholipid bilayer protects glutathione from degradation in the gastrointestinal tract

Elevation in the levels of oxidising molecules during oxidative stress disrupts the functioning of biological systems by extracting electrons from essential organic molecules, ultimately leading to cell damage and death due to ROS toxicity

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However, these TKIs also inhibited INSR due to a high level of sequence homology between IGF-1R and INSR-A/B kinase domains (220222) which may lead to adverse effects such as hyperinsulinemia (223)
