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When adverse effects do occur following high-dose B12 administration, they are typically mild, transient, and often related to the route of administration rather than the vitamin itself

Taken together, these results suggest that nuclear localization of FOXO4 may contribute to Leydig cell senescence and the downregulation of testosterone synthesis

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Despite these advances and their significant therapeutic potential, the molecular mechanisms underlying the potent cytoprotective effects of BPC157 remain largely undefined, limiting its full clinical translation

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