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In addition, the use of AKT inhibitors in combination with extracellular asparagine (ASN) depletion can significantly inhibit tumor growth (Fig
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10.14336/ad.2024.0586 [DOI] [PMC free article] [PubMed] [Google Scholar] Hu C., Zhao L., Tao J., Li L
When IGFBP-3 binds to IGF-1, it can reduce the concentration of free IGF, which is beneficial to play and magnify the role of IGF-1 and enhance the activity of IGF-1 receptor [28]
