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GHK-Cu, first identified in 1973 from mammalian plasma, functions as a naturally occurring copper-peptide complex that influences approximately 31% of the human genome, resetting gene expression patterns to favor tissue repair while delivering bioavailable copper essential for enzymatic processes underlying collagen synthesis and antioxidant defense

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Dale Bredesen was joined by Marama founder Dr

Moreover, Roti mitigated small intestinal injury by increasing Occludin and zonula occludens-1 (ZO-1) expression and decreasing TNF- and cyclooxygenase 2 (COX-2) expression