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120 Upon activation, Nrf2 is shuttled into the nucleus, where it binds to the antioxidant response element and enhances the expression of antioxidant genes

He required significant in-home nursing support, was no longer speaking, was frequently combative, and was occasionally delirious, i.e., much worse clinically than when undergoing prehyperbaric therapy and GSH precursors 7 months before

ROS initiate autophagy by activating the AMPK pathway and inhibiting the mTOR signal

4.5 Dietary supplements Certain fat-soluble vitamins have been demonstrated to possess the capacity to modulate ferroptosis

Eur J Nutr 43:191197