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The sulfhydryl (thiol)-containing tripeptide glutathione (GSH) is synthesized and maintained at high concentrations in virtually all cells and is one of the principal mechanisms by which reactive oxygen species (ROS) are eliminated [3, 7, 8]

Following withdrawal of NFT, Nrf2 levels rapidly declined below the detection limit, whereas GCLC levels remained significantly higher than those observed in the untreated control even after 24 h in the absence of NFT

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doi: 10.1016/j.nut.2022.111602