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Vora SM, Lieberman J, Wu H (2021) Inflammasome activation at the crux of severe COVID-19

Current clinical management primarily relies on immunosuppression therapy

Positively charged TMC coated AuNPs, acting as nanocarriers, interact with negatively charged siRNA via electrostatic interaction and form complexes

Publicly available datasets were analyzed in this study and can be found at hpap.pmacs.upenn.edu

Much of Noopept cognitive effect may be mediated through its metabolite cycloprolylglycine (cPG), which concentrates preferentially in the hippocampus and has been shown to reduce hippocampal cell death, increase BDNF mRNA, and modulate inflammatory cytokine expression