glutathione oxidative stress and neurodegeneration JCI Neurodegenerative Diseases: Potential Effect of

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thiamine hydrochloride (vitamin B1) (100 mg/mL)

Notably, the highest dose tested (54 mg) showed increased gastrointestinal event frequency compared to lower doses, suggesting a dose-relationship for this effect category

Raters observations were conducted in the context of the 100% likelihood of patients receiving an active drug in the 1-day regimen study vs 67% likelihood in the 21-day regimen study, which may have affected efficacy findings and AE reporting

Allergology international : official journal of the Japanese Society of Allergology 68(3):301308