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Together with the gut-associated lymphoid tissue and the neuroendocrine network, the intestinal epithelial barrier, with its intercellular tight junctions, controls the equilibrium between tolerance and immunity to nonself-antigens

Time frame and selection criteria: The focus was primarily on articles published in the last two decades, with particular attention to comprehensive reviews, landmark studies, and significant clinical trials

doi:10.3390/healthcare9020144 42

This synthetic analog of alpha-melanocyte stimulating hormone (alpha-MSH) produces skin darkening, increased libido, and appetite suppression

Overuse of growth hormonerelated peptides may impair glucose control, so dosing must be carefully managed