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The RGC-5 cells were treated exogenously with a mixture of three different GS(S) n SG: GSSSG (84%), GSSSSG (15%), and GSSSSSG (1%) (i.e., excluding GSSG) in the presence of hydrogen peroxide (H 2 O 2 ) after 15 hours of incubation with a glutathione synthesis inhibitor, buthionine sulphoximine (BSO) (Supplementary Figure S3)
Notably, by Day 8, animals treated with SIH contained total iron load on par with the untreated control group (Figure 3C
Eine parenterale Anwendung sollte deshalb klinisch berwacht werden, so eine narrative bersichtsarbeit aus dem Jahr 2025
Human HT-1080 fibroblasts are typical wild-type P53-expressing cells
