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The endogenous glutathione system serves as a vital intracellular and extracellular antioxidant that guards against oxidative and nitrosative stress while regulating inflammatory processes in the lungs [10]

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The present study provides the first evidence that babies born to mothers with thrombophilia in the second trimester of intrauterine life experience intense oxidative stress characterized by overproduction of O2., NO, ONOO, and LPO, as well as GSH depletion