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In particular, restoring immune balanceparticularly by promoting the polarization of macrophages toward the anti-inflammatory M2 phenotype and expanding the population of Tregshas emerged as a promising strategy for enhancing bone regeneration

doi: 10.1038/s41416-019-0650-z 13 PietkiewiczDKlupczynska-GabryszakAPlewaSMisiuraMHoralaAMiltykWet al

As a result, therapeutic interventions targeting metabolic pathways, including antioxidants such as GSH, may require reassessment in light of these evolving definitions

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[DOI] [PubMed] [Google Scholar] 20.Nawarskas J.J