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Cell Protection and Repair: By modulating cell adhesion molecules, it strengthens intercellular connections, promoting the repair of epithelial cells and connective tissue

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doi: 10.1016/j.immuni.2013.08.003 99 PircalabioruGAvielloGKubicaMZhdanovAPacletMHBrennanLet al

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However, direct cartilage injection of IGF-1 more effective than systemic elevation, and systemic growth hormone peptides produce modest IGF-1 increases (not pharmacological levels)