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Significant differences in the gene methylation patterns, however, were found between the group with prior COVID-19 and nave controls (Figure 10A)

2019 Jun;11(6):804-812

2018;22(3):384-397.e6

Zhang X, Johnson AD, Hendricks AE, Hwang S-J, Tanriverdi K, Ganesh SK et al (2014) Genetic associations with expression for genes implicated in GWAS studies for atherosclerotic cardiovascular disease and blood phenotypes

This further emphasizes the potential avenue for a significant improvement in a large proportion of stroke patient outcome where targeted thrombolytic intervention is modified based on time of onset (Figure 2)