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Even those who eventually tolerate high concentrations well typically experience problems when starting there
The standard method uses bacteriostatic water, added slowly down the side of the vial so the powder dissolves without foaming

Their effectiveness is supported by a large body of clinical research and real-world patient success

B12 shots are often prescribed by medical providers to treat B12 deficiencies and pernicious anemia

2008 Jun;29(Suppl):S177-87
