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31 (1), 1130 (2018) C

Fernando S, Wijewickrama A, Gomes L et al (2016) Patterns and causes of liver involvement in acute dengue infection

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In these contexts, astrocytes may shift from a neuroprotective role to one that exacerbates neuronal dysfunction, potentially due to downregulated expression of lactate dehydrogenase A (LDHA), a key glycolytic enzyme, which impairs lactate shuttling by inhibiting large conductance Ca 2+ activated potassium channel (BK channel)-mediated neuronal hyperpolarization (Yao et al., 2023)