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Another neurodegeneration condition is ataxia-telangiectasia (A-T), a disorder caused by mutations in the ataxia-telangiectasia-mutated (ATM) kinase gene

Rimassa L, Assenat E, Peck-Radosavljevic M, Pracht M, Zagonel V, Mathurin P, et al

In all three AMYRs, P37 Cagri and Y37 rAmy occupy the same pocket above W79 ECD of the CTR ECD where they form conserved interactions with surrounding residues (Fig

The effects might be additive, synergistic, or potentially counteractive depending on specific circumstances

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