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Over time, these crystals trigger gout flare-ups or gout attacks, leading to intense pain, redness, and swelling

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In this context, NSAIDs, for example, are widely employed owing to their ability to inhibit cyclooxygenase (COX-1 and COX-2) enzymes

the Patchells daughter and middle child, Mary, was baptized in the Episcopal Church on July 2, 1876

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