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86 Some evidence suggests individuals with MTHFR polymorphisms may need higher doses of folic acid to experience therapeutic benefits and may respond better to supplementation with 5-methyltetrahydrofolate (5-MTHF), the active form of this B vitamin

Yu HM, Wang TC

Influence of ejaculatory abstinence on seminal total antioxidant capacity and sperm membrane lipid peroxidation
This translates to more glutathione reaching your cells where it can actively neutralize free radicals, support detoxification, and boost your immune system

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