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Description
Although our data suggest that production of NADPH by the TCA cycle is a key event in our proposed pathway, it is not yet clear how NADPH production corresponds to actual activity of the cyclegiven that metabolites can enter and exit the cycle at multiple points depending on nutritional conditionsor how the cellular compartmentalization of NADPH production contributes to the transmission of the NADPH status to the glutathione system
And then, the physical change happened
AO, ascorbate oxidase

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In the satellite facility, 16 mice were aged until they reached 90 weeks of age when they underwent cognitive testing
