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Inhibition of the BCL-2 pathway induced apoptosis of some senescent cell types, such as mouse and human fibroblasts, HUVECs, as well as cells of the lung and epidermis, but not primary human preadipocytes (60, 61)

Any references to tissue, vascular, or gastrointestinal models are provided only for research context and do not imply therapeutic or clinical use

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