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PGC-1 exerts its regulatory effects by coactivating several transcription factors, including PPARs, estrogen-related receptor- (ERR), FOXO1, hepatocyte nuclear factor 4 (HNF4), and nuclear respiratory factors (NRFs) (Fig
But its production may not meet the needs under certain conditions such as increased energy demands and therefore it is considered a onditionally essential nutriention
The genes CntA/B have been detected in the genus Acinetobacter (e.g
Genetics, food, illness conditions, and environmental variables all influence the composition of the gut microbiota
