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The PK parameters showed dose-proportionality, with a short terminal half-life of 2 hours, a clearance of 0.078 L/h/kg and a volume of distribution at steady-state of 0.22 L/kg

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The peptide activates transforming growth factor-beta (TGF-) signaling cascades, leading to enhanced collagen I and III synthesis through increased procollagen C-proteinase activity

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