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10.1016/j.conb.2012.02.005 Curr

One mechanism is through disruption of calcium channels and pumps (e.g., voltage-gated calcium channels (VGCCs), receptor-operated calcium channels, store-operated calcium channels, transient receptor-potential ion channels, and Ca 2+ -ATPase) [28, 37]

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Collectively, these mechanisms underscore the role of the gut microbiota as an active modulator of PD pathogenesis

It is estimated that more than 47 million individuals suffer from dementia globally, and the figure is expected to increase to 150 million by 2050 [78, 79]
