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Additionally, the contribution of curcumin in posterior capsule opacification attenuation has been suggested, considering its ability to inhibit proliferation and epithelialmesenchymal transition by different pathways [101,102]

Nevertheless, owing to the concomitant upregulation of CTLA-4 and differential RT sensitivities among immune cells in the TME 53,54 , we speculated that the ratio of CD8 + T/Treg would be decreased in tumors due to the stronger radioresistance of Treg than CD8 + T cells (Fig

This bidirectional interplay between systems contributes to a robust and layered antioxidant defense network

The GSH/GSSG ratio maintains ~100:1 at steady state but decreases to 10:1 or less under oxidative stress

Sections were stained with Ehrlichs hematoxylin and counterstained with eosin after Tousson (2016) 36