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It was highlighted that inducible activation of Nrf2 promotes cytoprotective mechanisms against various immune, neurodegenerative, and metabolic disorders characterized by OS and inflammation

[DOI] [PubMed] [Google Scholar] 85.Cossart P., Helenius A

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These hepatic pathological changes in OXA-induced ALI were different from the pathology of chronic liver injuries induced by multi-cycle OXA-based chemotherapy reported in clinical observation and animal studies, in which the primary characteristics of liver injury are liver sinusoidal injury and SOS (2,3)

For the tumour relapse experiments (Fig