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In experiments conducted on animals, it has been observed that the function of epidermal stem cells is impaired when telomeres undergo shortening ( Senescent cells can perturb their microenvironment by directly secreting senescence-related factors or by utilizing other means of communication, such as extracellular vesicles, leading to functional degradation ( Fibroblasts obtained from naturally aged skin elevate the synthesis of cysteine-rich protein 61 (CCN1), which impairs the balance of collagen and results in skin dysfunction

According to Italian researchers from the Department of Experimental Medicine, Section of General Pathology (Genoa) , glutathione deficiency causes cells to be more vulnerable to oxidative stress, which contributes to cancer development

This modality, however, comes with inherent risks of transmitting fecal-oral infectious agentsbacterial, viral, and fungalfrom donor to recipient

Conversely, the probiotic cow yogurt group showed decreased levels of family Erysipelotrichaceae, Clostridiaceae , genus Oscillospira , Clostridium, Ruminococcus, Aerococcus , species Ruminococcus gnavus and Clostridium perfringens compared to the regular cow yogurt group