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Almost 200 years later in 1885, Paul Ehrlich observed that the trypan blue dye, when given in the blood circulation in rats, stained only peripheral organs not the brain and spinal cord [1, 2]

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Biological Trace Element Research, pp 115 Mocchegiani E, Romeo J, Malavolta M, Costarelli L, Giacconi R, Diaz L-E, Marcos A (2013) Zinc: dietary intake and impact of supplementation on immune function in elderly

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