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At this point, it should be mentioned that although there are at least three biological replicates for all experiments, the actual number of some experiments was much higher due to different experimental read-outs

Cysteine bioavailability: main players and regulators As mentioned above, the bioavailability of cysteine in a cancer cell can influence metabolic fitness and the development of therapy resistance

The tendency reported in the different studies is not always consistent, increasing in some studies, while decreasing in others

MOTS-c Strength: 10 mg Mitochondrial-derived peptide A performance and energy-oriented peptide option frequently associated with metabolic resilience support

This is consistent with the hypothesis that the cell has an over-capacity to chelate metal [208]