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In the first 2 to 4 weeks, subtle changes are typical rather than dramatic before-and-after results

Metabolite production was quantified by LC/MS/MS API3000 and normalized to total cell protein

Hunter, K

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To determine which proteoforms may be associated with pathological and cognitive diagnosis on a continuous scale, avoiding subjective between-class limits, parallel linear models were fit with quantification ratio of each peptide as outcome variables, and global cognition Z-score, global pathology Z-score, age at death, sex, post-mortem interval (hours) and number of years in education as explanatory variables