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The main cause of hyperhomocysteinemia is a redox imbalance leading to oxidative stress characterized by an accumulation of oxidized GSH followed by an impairment of cellular integrity and kidney homeostasis

More than genes and cells: Drug discovery in the extracellular matrix (ECM)

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Since mitochondria are highly compartmentalized organelles requiring specific transporters for the movement of metabolites and molecules, the transportation of endogenously expressed MOTS-c within organelles by transporters such as SLC25 family and between cells or tissues require further investigation

TB-500: The Inflammation Controller TB-500 is a synthetic fragment of thymosin beta-4, a peptide naturally produced by the thymus gland